Biopharmaceutics & Drug Disposition publishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs.
These include:
? animal and human pharmacological studies that focus on therapeutic response, pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites
? in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in human
? studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition
? simulation and modeling in drug discovery and development
? theoretical treatises
Biopharmaceutics & Drug Disposition刊發(fā)有關(guān)生物藥劑學(xué)、藥物處置、藥代動(dòng)力學(xué)和藥效學(xué)的原創(chuàng)性研究、綜述與簡(jiǎn)報(bào)，尤其是與藥物研發(fā)和藥物治療相關(guān)的文章。感興趣的主題包括：動(dòng)物和人體藥理學(xué)研究，側(cè)重于與藥物及其代謝物的血漿和組織濃度相關(guān)的治療反應(yīng)、藥效學(xué)和毒性；體外和體內(nèi)藥物吸收、分布、代謝、轉(zhuǎn)運(yùn)和排泄研究，促進(jìn)與人類(lèi)藥物使用相關(guān)的研究；關(guān)于膜轉(zhuǎn)運(yùn)和酶的研究，包括其調(diào)控以及藥物基因組學(xué)對(duì)藥物吸收和處置的影響；藥物發(fā)現(xiàn)和開(kāi)發(fā)中的模擬和建模等。
